Home/Pharmaceutical excipient: Bismuth aluminate hydrate

Essential information of bismuth aluminate hydrate


Bismuth aluminate hydrate (CAS: 308796-32-9) is a kind of pharmaceutical excipient. Its appearance is white or off-white powder, no smell or taste, undissolved in water or ethanol. The synonyms of bismuth aluminate hydrate have aluminum bismuth oxide hydrate, trialuminium bismuth hexaoxide hydrate, bismuth(3+) tris(oxoalumanolate). It need to be stored in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Application of bismuth aluminate hydrate

Bismuth aluminate hydrate (CAS: 308796-32-9) is generally and immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. Aluminates are compounds with a negatively-charged alumina ion and a metallic oxide with various industrial applications such as water treatment and ceramics manufacturing. American elements produce to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards. Typical and custom packaging is available. Additional technical, research and safety (MSDS) information is available as is a reference calculator for converting relevant units of measurement.

Pharmaceutical excipient: Bismuth aluminate hydrate

As we all know, a rule medicament utilized for fighting gastric diseases must produce a stomachal dressing when ulcers are present, and in certain cases an intestinal action. Bismuth salts are used most frequently, chiefly carbonate and sub-nitrate. Alumina salts have also been proposed and this substance usually gives good results where bismuth is unsuccessful, and viceversa. It was with a view to associate the activity of alumina with that of bismuth that the applicant thought of combining the oxides of these two substances in predetermined proportions and in a physical state also predetermined in view of deriving the maximal therapeutic action therefrom. The use of hydrated aluminum oxide on the one hand and hydrated bismuth oxide on the other hand was chiefly confined to the use of freshly prepared products forming a suspension in a suitable liquid medium up to now. Apparently, this is due to the fact that these products cannot lose the major portion of their hydration water without contracting and hardening, so that when ground they yield but a relatively dense powder scarcely adapted to spread over and cover the walls of the digestive system. The applicant has discovered and developed a method whereby an intimate mixture having a predetermined composition may be prepared from hydrated aluminum oxide and hydrated bismuth oxide at present , this mixture being not contractible and enabling an extremely light powder to be produced which is characterized by an exceptional surface-covering powder.